Tenofovir-diphosphate
Tenofovir-DP, Sodium salt
[2-(6-Amno-9H-purin-9-yl)-1-methylethoxy]methyl-triphosphate; [(1R)-2-(6-aminopurin-9-yl)-1-methyl-ethoxy]methyl-[hydroxy(phosphonooxy)phosphoryl]oxy-phosphinic acid
PMPApp
| Catálogo Nº | Apresentação | Preço (R$) | Comprar / Observação |
|---|---|---|---|
| NU-975 | 1 mg | Sob demanda | Adicionar ao Carrinho |
For general laboratory use.
Envio: shipped on gel packs
Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Validade: 12 months after date of delivery
Fórmula molecular: C9H16N5O10P3 (free acid)
Peso molecular: 447.17 g/mol (free acid)
CAS#: 166403-66-3
Pureza: ≥ 95 % (HPLC)
Forma: solid
Propriedades espectroscópicas: λmax 259 nm, ε 15.4 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Referências selecionadas:
Zheng et al. (2016) Application of an intracellular assay for determination of Tenofovir-diphosphate and Emtricitabine-triphosphate from erythrocytes using Dried Blood Spots. J. Pharm. Biomed. Anal. 122:16.
Dickinson et al. (2015) Plasma Tenofovir, Emtricitabine, and Rilpivirine and Intracellular Tenofovir Diphosphate and Emtricitabine Triphosphate Pharmacokinetics following Drug Intake Cessation. Antimicrob. Agents Chemother. 59 (10):6080.