Acyclovir-5'-triphosphate

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 12 months after date of delivery

Fórmula molecular: C8H14N5O12P3 (free acid)

Peso molecular: 465.14 g/mol (free acid)

CAS#: 66341-18-2

Pureza: ≥ 95 % (HPLC)

Forma: solid

Propriedades espectroscópicas: λmax 252 nm, ε 13.7 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Referências selecionadas:
Keller et al. (2008) Interaction of Herpes Primase with the Sugar of a NTP. Biochemistry 47 (34):8977.

Hanes et al. (2007) Enzymatic Therapeutic Index of Acyclovir: Viral versus human polymerase γ specificity. Journal of Biological Chemistry 282 (34):25159.

Huang et al. (1999) The enzymological basis for resistance of herpesvirus DNA polymerase mutants to acyclovir: relationship to the structure of α -like DNA polymerases. Proceedings of the National Academy of Sciences of the United States of America 96 (2):447.