Ganciclovir-triphosphate
Sodium salt
GCV-TP
9-(1,3-Dihydroxy-2-propoxymethyl)guanine-5'-triphosphate
| Catálogo Nº | Apresentação | Preço (R$) | Comprar |
|---|---|---|---|
| NU-275S | 10 μl (100 mM) | Sob demanda | Adicionar ao Carrinho |
| NU-275L | 5 x 10 μl (100 mM) | Sob demanda | Adicionar ao Carrinho |
For general laboratory use.
Envio: shipped on gel packs
Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Validade: 12 months after date of delivery
Fórmula molecular: C9H16N5O13P3 (free acid)
Peso molecular: 495.17 g/mol (free acid)
Pureza: ≥ 95 % (HPLC)
Forma: solution in water
Concentração: 100 mM - 110 mM
pH: 7.5 ±0.5
Propriedades espectroscópicas: λmax 252 nm, ε 13.6 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Referências selecionadas:
Davis et al. (2007) Hypoxia Enhances the Phosphorylation and Cytotoxicity of Ganciclovir and Zidovudine in Kaposi's Sarcoma-Associated Herpesvirus–Infected Cells. Cancer Res. 67:7003.
Zhu et al. (2005) Potent Antiviral Activity of North-Methanocarbathymidine against Kaposi's Sarcoma-Associated Herpesvirus. Antimicrob. Agents Chemother. 49:4965.
Rubsam et al. (1999) Cytotoxicity and accumulation of ganciclovir triphosphate in bystander cells cocultured with herpes simplex virus type 1 thymidine kinase-expressing human glioblastoma cells. Cancer Res. 59:669.