3TCMP

Lamivudine monophosphate, Sodium Salt (L-Isomer)

2', 3'-Dideoxy-3'-thia-cytidine-5'-monophosphate, Sodium salt (L isomer)

Lamivudine monophosphate, Sodium Salt (L-Isomer)

Catálogo Nº Apresentação Preço (R$) Comprar
NU-1605S 10 μl (10 mM)Sob demanda Adicionar ao Carrinho
NU-1605L 5 x 10 μl (10 mM)Sob demanda Adicionar ao Carrinho
Structural formula of 3TCMP (Lamivudine monophosphate, Sodium Salt (L-Isomer), 2', 3'-Dideoxy-3'-thia-cytidine-5'-monophosphate, Sodium salt (L isomer))
Structural formula of 3TCMP

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 12 months after date of delivery

Fórmula molecular: C8H12N3O6PS (free acid)

Peso molecular: 309.23 g/mol (free acid)

Pureza: ≥ 95 % (HPLC)

Forma: solution in water

Concentração: 10 mM - 11 mM

pH: 7.5 ±0.5

Propriedades espectroscópicas: λmax 270 nm, ε 9.5 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Referências selecionadas:
Coulier et al. (2008) Simultaneous determination of endogenous deoxynucleotides and phosphorylated nucleoside reverse transcriptase inhibitors in peripheral blood mononuclear cells using ion-pair liquid chromatography coupled to mass spectrometry. Proteomics Clin. Appl. 2:1557.

Mas et al. (2002) Multidrug-resistant HIV-1 reverse transcriptase: involvement of ribonucleotide-dependent phosphorolysis in cross-resistance to nucleoside analogue inhibitors. J. Mol. Biol. 323:181.