2'OMe-UTP
2'-O-Methyluridine-5'-triphosphate, Sodium salt
| Catálogo Nº | Apresentação | Preço (R$) | Comprar |
|---|---|---|---|
| NU-1212S | 50 μl (100 mM) | Sob demanda | Adicionar ao Carrinho |
| NU-1212L | 5 x 50 μl (100 mM) | Sob demanda | Adicionar ao Carrinho |
For general laboratory use.
Envio: shipped on gel packs
Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Validade: 12 months after date of delivery
Fórmula molecular: C10H17N2O15P3 (free acid)
Peso molecular: 498.17 g/mol (free acid)
Pureza: ≥ 95 % (HPLC)
Forma: solution in water
Concentração: 100 mM - 110 mM
pH: 7.5 ±0.5
Propriedades espectroscópicas: λmax 262 nm, ε 10.1 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Referências selecionadas:
Lauridsen et al. (2012) Enzymatic recognition of 2'-modified ribonucleoside 5'-triphosphates: towards the evolution of versatile aptamers. Chembiochem. 13 (1):19.
Xiao et al. (2012) Engineering of Targeted Nanoparticles for Cancer Therapy Using Internalizing Aptamers Isolated by Cell-Uptake Selection. ACS Nano 6 (1):696.
Keefe et al. (2008) SELEX with modified nucleotides. Curr. Opin. Chem. Biol. 12 (4):448.
Burmeister et al. (2006) 2'-Deoxy purine, 2'-O-methyl pyrimidine (dRmY) aptamers as candidate therapeutics. Oligonucleotides 16 (4):337.
Burmeister et al. (2005) Direct in vitro selection of a 2'-O-methyl aptamer to VEGF. Chem. Biol. 12 (1):25.