REP-2His

Rab Escort Protein

human, recombinant, Saccharomyces cerevisiae

Catálogo Nº Apresentação Preço (R$) Comprar / Observação
PR-104 50 μg Sob demanda Adicionar ao Carrinho

For general laboratory use.

Envio: shipped on dry ice

Condições de armazenamento: store at -80 °C
avoid freeze/thaw cycles

Validade: 12 months

Número de acesso: NM_001821

Número de acesso: NM_001821

Pureza: > 90 % (SDS-PAGE)

Forma: liquid (Supplied in 25 mM HEPES pH 7.2, 40 mM NaCl and 10 mM DTT)

Atividade: 1 pmol of REP-2 will mediate transfer of 2 pmol of geranylgeraniol by RabGGTase onto 1 pmol of Rab7 in 3 minutes.

Descrição:
C-terminal His-tagged REP-2 (Rab escort protein-2) binds to a wide range of RabGGTase with nanomolar affinities and supports the prenylation of RabGTPase mediated by RabGGTase, with an exception of Rab27.

Referências selecionadas:
Cremers et al. (1994) REP-2, a Rab escort protein encoded by the choroideremia-like gene. J. Biol. Chem. 269:2111.