Rab34GST-His
Ras-associated, small GTP-binding protein
human, recombinant, E. coli
| Catálogo Nº | Apresentação | Preço (R$) | Comprar / Observação |
|---|---|---|---|
| PR-195 | 50 μg | Sob demanda | Adicionar ao Carrinho |
For in vitro use only!
Envio: shipped on dry ice
Condições de armazenamento: store at -80 °C
avoid freeze/thaw cycles
Validade: 12 months
Peso molecular: 58 kDa
Número de acesso: AAH66904
Número de acesso: AAH66904
Pureza: > 90 % (SDS-PAGE)
Forma: liquid (Supplied in 25 mM HEPES pH 7.2, 40 mM NaCl and 5 mM mercaptoethanol)
Atividade: 100 pmol of protein can bind > 80 pmol of GDP.
Descrição:
N-terminal tagged Rab34 is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. The small GTPase Rab 34 is restricted to cell surface membrane ruffles and lysosmes. It regulates the spatial distribution of lysosomes and is required for formation of macropinosomes. The GST-Tag facilitates the protein`s application in typical GST pull-down assays.
Referências selecionadas:
Stenmark et al. (2001) The Rab GTPase family. Genome Biol. 2:30071.
Yamaguchi et al. (2002) A GDP/GTP exchange protein for the Rab3 small G protein family up-regulates a postdocking step of synaptic exocytosis in central synapses. Proc. Natl. Acad. Sci. USA. 99:14536.