Rab32
Ras-associated, small GTP-binding protein
human, recombinant, E. coli
| Catálogo Nº | Apresentação | Preço (R$) | Comprar / Observação |
|---|---|---|---|
| PR-194 | 50 μg | Sob demanda | Adicionar ao Carrinho |
For general laboratory use.
Envio: shipped on dry ice
Condições de armazenamento: store at -80 °C
avoid freeze/thaw cycles
Validade: 12 months
Número de acesso: NP_006825
Número de acesso: NP_006825
Pureza: > 90 % (SDS-PAGE)
Forma: liquid (Supplied in 25 mM Hepes pH 7.2, 40 mM NaCl, 2 mM MgCl2, 10 μM GDP and 1 mM β-mercaptoethanol)
Atividade: 100 pmol of protein can bind > 80 pmol of GDP.
Descrição:
Rab32 is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. Rab 32 is localized in perinuclear vesicles and mitochondria and regulates melanosome transport and mitochondrial fission.It may participate in adaptation to changing energy requirements during growth.
Referências selecionadas:
Stenmark et al. (2001) The Rab GTPase family. Genome Biol. 2:30071.
Yamaguchi et al. (2002) A GDP/GTP exchange protein for the Rab3 small G protein family up-regulates a postdocking step of synaptic exocytosis in central synapses. Proc. Natl. Acad. Sci. USA. 99:14536.