Rab23
Ras-associated, small GTP-binding protein
mouse, recombinant, E. coli
| Catálogo Nº | Apresentação | Preço (R$) | Comprar / Observação |
|---|---|---|---|
| PR-191 | 50 μg | Sob demanda | Adicionar ao Carrinho |
For general laboratory use.
Envio: shipped on dry ice
Condições de armazenamento: store at -80 °C
avoid freeze/thaw cycles
Validade: 12 months
Número de acesso: NP_033025
Número de acesso: NP_033025
Pureza: > 90 % (SDS-PAGE)
Forma: liquid (Supplied in 50 mM Tris-HCl pH 8.0, 100 mM NaCl, 10 mM MgCl2, 10 μM GDP and 2 mM mercaptoethanol)
Atividade: 100 pmol of protein can bind > 80 pmol of GDP.
Descrição:
Rab23 is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. Rab 23 is expressed at high levels in brain and locolized to plasma membrane and endosomes. It regulates ciliary and sonic hedgehog signalling pathways and is involved in embryogenesis.
Referências selecionadas:
Stenmark et al. (2001) The Rab GTPase family. Genome Biol. 2:30071. Yamaguchi et al. (2002) A GDP/GTP exchange protein for the Rab3 small G protein family up-regulates a postdocking step of synaptic exocytosis in central synapses. Proc. Natl. Acad. Sci. USA. 99:14536.