Rab1BGST-His
Ras-associated, small GTP-binding protein
rat, recombinant, E. coli
| Catálogo Nº | Apresentação | Preço (R$) | Comprar / Observação |
|---|---|---|---|
| PR-114 | 50 μg | Sob demanda | Adicionar ao Carrinho |
For general laboratory use.
Envio: shipped on dry ice
Condições de armazenamento: store at -80 °C
avoid freeze/thaw cycles
Validade: 12 months
Peso molecular: 52 kDa
Número de acesso: X13905
Número de acesso: X13905
Pureza: > 90 % (SDS-PAGE)
Forma: liquid (Supplied in 50 mM Tris-HCl pH 8.0, 200 mM NaCl, 2 mM MgCl2, 10 μM GDP and 2 mM beta-mercaptoethanol)
Atividade: 100 pmol of protein can bind > 80 pmol of GDP.
Descrição:
Rab1B is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. For example, Rab1A (cat.# PR-113), Rab1B, and Rab2 (cat.# PR-111, PR-112) are located in the ER to Golgi intermediate compartment and cis Golgi cisternae and are required for ER to Golgi and intra Golgi transport. The GST-Tag facilitates the protein`s application in typical GST pull-down assays.
Referências selecionadas:
Stenmark et al. (2001) The Rab GTPase family. Genome Biol. 2:30071. Plutner et al. (1991) Rab1b regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. J. Cell Biol. 115:31. Jin et al. (1996) Rab1a and multiple other Rab proteins are associated with the transcytotic pathway in rat liver. J. Biol. Chem. 271:30105.