RabGDI

Rab GDP Dissociation Inhibitor, member of Ras oncogene family

bovine, recombinant, Sf9 insect cells

Catálogo Nº Apresentação Preço (R$) Comprar / Observação
PR-110 50 μg Sob demanda Adicionar ao Carrinho

For general laboratory use.

Envio: shipped on dry ice

Condições de armazenamento: store at -80 °C
avoid freeze/thaw cycles

Validade: 12 months

Número de acesso: 1GND

Número de acesso: 1GND

Pureza: > 90 % (SDS-PAGE)

Forma: liquid (Supplied in 40 mM HEPES pH 7.2, 50 mM NaCl, 100 μM GDP and 3 mM DTE)

Descrição:
Rab GDP Dissociation Inhibitor (RabGDI) forms complexes with cytosolic prenylated GDP-bound Rab proteins and delivers them to the target membrane.It also retreaves GDP-bound Rab proteins from the membrane releases.

Referências selecionadas:
Horiuchi et al. (1995) A GDP/GTP exchange-stimulatory activity for the Rab5-RabGDI complex on clathrin-coated vesicles from bovine brain. J. Biol. Chem. 270:11257. Ullrich et al. (1993) Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins. J. Biol. Chem. 168:18143.