B-GPP
Biotin-labeled geranyl pyrophosphate, triethylammonium salt
| Catálogo Nº | Apresentação | Preço (R$) | Comprar / Observação |
|---|---|---|---|
| LI-015 | 20 μl | Sob demanda | Adicionar ao Carrinho |
For general laboratory use.
Envio: shipped on gel packs
Condições de armazenamento: store at -20 °C
avoid freeze/thaw cycles
Validade: 12 months
Fórmula molecular: C20H35N3O9P2S
Peso molecular: 555.52 g/mol
Pureza: mass identification conforms (ESI-MS)
Forma: liquid (Supplied as 1 mM solution in 25 mM (NH4)2CO3)
Concentração: 1 mM
Descrição:
B-GPP is a biotin-labeled analog of geranyl pyrophosphate (GPP). It serves as lipid donor for the native RabGGTase and mutants of GGTase-I and FTase. B-GPP allows for straightforward mammalian prenylome labeling and thus, not only identifying protein prenyltransferase substrates but efficiently screening for new inhibitors.
Referências selecionadas:
Kovtun et al. (2010) Towards the construction of expressed proteomes using a Leishmania tarentolae based cell-free expression system. PLoS One. 5 (12):e14388.
Nguyen et al. (2009) Analysis of the eukaryotic prenylome by isoprenoid affinity tagging. Nature Chemical Biology. 5 (4):227.