5-Iodo-UDP

(5I-UDP)

5-Iodo-uridine-5'-diphosphate, Sodium salt

Catálogo Nº Apresentação Preço (R$) Comprar
NU-867S 50 μl (10 mM)Sob demanda Adicionar ao Carrinho
NU-867L 5 x 50 μl (10 mM)Sob demanda Adicionar ao Carrinho
Structural formula of 5-Iodo-UDP ((5I-UDP), 5-Iodo-uridine-5'-diphosphate, Sodium salt)
Structural formula of 5-Iodo-UDP

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 12 months after date of delivery

Fórmula molecular: C9H13N2O12P2I (free acid)

Peso molecular: 530.06 g/mol (free acid)

CAS#: 34198-43-1

Pureza: ≥ 95 % (HPLC)

Forma: solution in water

Concentração: 10 mM - 11 mM

pH: 7.5 ±0.5

Propriedades espectroscópicas: λmax 287 nm, ε 7.7 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Specific Ligands:

Selective agonistic ligand for P2Y6 receptor[1,2,3]

Referências selecionadas:
[1] Besada et al. (2006) Structure-activity relationships of uridine-5'-diphosphate analogues at the human P2Y6 receptor. J. Med. Chem. 49 (18):5532.

[2] Mamedova et al. (2008) Attenuation of apoptosis in vitro and ischemia/reperfusion injury in vivo in mouse skeletal muscle by P2Y6 receptor activation. Pharmacol. Res. 58 (3-4):232.

[3] Jacobson et al. (2009) Development of selective agonists and antagonists of P2Y receptors. Purinergic Signalling 5:75.