AMP - Solid

Adenosine-5'-monophosphate, Sodium salt

Catálogo Nº Apresentação Preço (R$) Comprar
NU-1025-5G 5 gSob demanda Adicionar ao Carrinho
NU-1025-25G 25 gSob demanda Adicionar ao Carrinho
Structural formula of AMP - Solid (Adenosine-5'-monophosphate, Sodium salt)
Structural formula of AMP - Solid

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 12 months after date of delivery

Fórmula molecular: C10H14N5O7P (free acid)

Peso molecular: 347.22 g/mol (free acid)

CAS#: 4578-31-8

Pureza: ≥ 95 % (HPLC)

Forma: solid

Propriedades espectroscópicas: λmax 259 nm, ε 15.4 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Formulários:
Agonistic ligand, mainly for nucleoside receptor A2Aan less to A3
After dephosphorylation by different membrane-bound phosphatases the formed adenosine can directly activate the receptor.

Referências selecionadas:
Volonte et al. (2009) Membrane components and purinergic signalling: the purinome, a complex interplay among ligands, degrading enzymes, receptors and transporters. FEBS J. 276:318.

Yegutkin (2008) Nucleotide and nucleoside converting enzymes: Important modulators of purinergic signalling cascade. Biochim. Biophys. Acta 1783:673.

Van Galen et al. (1994) A binding site model and structure-activity relationships for rat A3 adenosine receptor. Molecular Pharmacology 45:1101.

Williams et al. (1986) Effects of purine nucleotides on the binding of [3H]cyclopentyladenosine to adenosine A1-receptors in rat brain membranes. J. Neurochem. 47 (1):88.