dTpNHpp

(dTMPNPP)

2'-Deoxythymidine-5'-[(α,β)-imido]triphosphate, Sodium salt

Catálogo Nº Apresentação Preço (R$) Comprar / Observação
NU-907-1 1 mg Sob demanda Adicionar ao Carrinho
Structural formula of dTpNHpp ((dTMPNPP), 2'-Deoxythymidine-5'-[(α,β)-imido]triphosphate, Sodium salt)
Structural formula of dTpNHpp

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 12 months after date of delivery

Fórmula molecular: C10H18N3O13P3 (free acid)

Peso molecular: 481.18 g/mol (free acid)

CAS#: 141171-14-4 (free acid)

Pureza: ≥ 95 % (HPLC)

Forma: solid

Propriedades espectroscópicas: λmax 267 nm, ε 9.6 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Referências selecionadas:
Koag et al. (2019) Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases. J. Am. Chem. Soc. 141 (11):4584.

Ma et al. (2008) New thymidine triphosphate analogue inhibitors of human immunodeficiency virus-1 reverse transcriptase. J. Med. Chem. 35 (11):1938.