GppNH2

(GMPPN)

Guanosine-5'-(β-amino)-diphosphate, Sodium salt

Catálogo Nº Apresentação Preço (R$) Comprar
NU-1136S 150 μl (10 mM)Sob demanda Adicionar ao Carrinho
NU-1136L 5 x 150 μl (10 mM)Sob demanda Adicionar ao Carrinho
Structural formula of GppNH2 ((GMPPN), Guanosine-5'-(β-amino)-diphosphate, Sodium salt)
Structural formula of GppNH2

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 12 months after date of delivery

Fórmula molecular: C10H16N6O10P2 (free acid)

Peso molecular: 442.22 g/mol (free acid)

Pureza: ≥ 95 % (HPLC)

Forma: solution in water

Concentração: 10 mM - 11 mM

pH: 7.5 ±0.5

Propriedades espectroscópicas: λmax 252 nm, ε 13.7 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Referências selecionadas:
Rudolph et al. (1999) Nucleotide binding to the G12V-mutant of Cdc42 investigated by X-ray diffraction and fluorescence spectroscopy: two different nucleotide states in one crystal. Protein Sci. 8 (4):778.

Ott et al. (1989) Guanine nucleotide-mediated inhibition of opioid agonist binding. Modulatory effects of ions and of receptor occupancy. Biochem Pharmacol. 38 (12):1931.

Eckstein et al. (1975) Synthesis of guanosine 5'-di- and -triphosphate derivatives with modified terminal phosphates: effect on ribosome-elongation factor G-dependent reactions. Biochemistry 14 (23):5225.