5-Bromo-UMP

(5Br-UMP)

5-Bromo-uridine-5'-monophosphate, Sodium salt

Catálogo Nº Apresentação Preço (R$) Comprar
NU-135S 100 μl (10 mM)Sob demanda Adicionar ao Carrinho
NU-135L 5 x 100 μl (10 mM)Sob demanda Adicionar ao Carrinho
Structural formula of 5-Bromo-UMP ((5Br-UMP), 5-Bromo-uridine-5'-monophosphate, Sodium salt)
Structural formula of 5-Bromo-UMP

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 12 months after date of delivery

Fórmula molecular: C9H12BrN2O9P (free acid)

Peso molecular: 403.08 g/mol (free acid)

CAS#: 2149-79-3

Pureza: ≥ 95 % (HPLC)

Forma: solution in water

Concentração: 10 mM - 11 mM

pH: 7.5 ±0.5

Propriedades espectroscópicas: λmax 278 nm, ε 9.7 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Referências selecionadas:
Labesse et al. (2011) Structural and functional characterization of the Mycobacterium tuberculosis uridine monophosphate kinase: insights into the allosteric regulation. Nucleic Acids Res. 39 (8):3458.

Gilles et al. (2007) Regulatory Mechanisms Differ in UMP Kinases from Gram-negative and Gram-positive Bacteria. J. Biol. Chem. 282 (10):7242.

Kwon et al. (1999) Bipartite modular structure of intrinsic, RNA hairpin-independent termination signal for phage RNA polymerases. J. Biol. Chem. 274 (41):29149.

Tourneux et al. (1998 ) Substitution of an alanine residue for glycine 146 in TMP kinase from Escherichia coli is responsible for bacterial hypersensitivity to bromodeoxyuridine. J. Bacteriol. 180 (16):4291.