2'-Iodo-dATP

(2'I-dATP)

2'-Iodo-2'-deoxyadenosine-5'-triphosphate, Sodium salt

Catálogo Nº Apresentação Preço (R$) Comprar / Observação
NU-101 150 μl (10 mM) Sob demanda Adicionar ao Carrinho
Structural formula of 2'-Iodo-dATP ((2'I-dATP), 2'-Iodo-2'-deoxyadenosine-5'-triphosphate, Sodium salt)
Structural formula of 2'-Iodo-dATP

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 12 months after date of delivery

Fórmula molecular: C10H15N5O12P3I (free acid)

Peso molecular: 617.08 g/mol (free acid)

CAS#: 107245-25-0

Pureza: ≥ 95 % (HPLC)

Forma: solution in water

Concentração: 10 mM - 11 mM

pH: 7.5 ±0.5

Propriedades espectroscópicas: λmax 259 nm, ε 15.4 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Referências selecionadas:
Liu et al. (2011) Initiation complex structure and promoter proofreading. Science 333 (6042):633.

Gruen et al. (1999) 2'-Halo-ATP and -GTP analogues: Rational phasing tools for protein crystallography. Protein Sci. 8:2524.

Gruen et al. (1999) Synthesis of 2'-iodo- and 2'-bromo-ATP and GTP analogues as potential phasing tools for X-ray crystallography. Nucleos. Nucleot.18 (1):137.

Naber et al. (1995) A novel adenosine-triphosphate analog with a heavy-atom to target the nucleotide-binding site of proteins. Protein Sci. 4:1824.