ATP-acetyl-Desthiobiotin

Desthiobiotin-ATP probe

Desthiobiotin-acyl-ATP (DBAcATP)

Tri(triethylammonium) salt

Catálogo Nº Apresentação Preço (R$) Comprar / Observação
NU-276 16 x 0.01 μmol (16 x approximately 10.1 μg) Sob demanda Adicionar ao Carrinho
Structural formula of ATP-acetyl-Desthiobiotin (Desthiobiotin-ATP probe, Tri(triethylammonium) salt)
Structural formula of ATP-acetyl-Desthiobiotin

For general laboratory use.

Envio: shipped on dry ice

Condições de armazenamento: store at -80 °C

Validade: 6 months after date of delivery

Fórmula molecular: C20H32N7O15P3 (free acid)

Peso molecular: 703.43 g/mol (free acid)

Pureza: ≥ 75 % (HPLC)

Forma: solid

Propriedades espectroscópicas: λmax 259 nm, ε 15.3 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Please note:
Minimize exposure of the product to ambient temperature and store unused product at -80 °C.Avoid repeated freeze/thaw cycles.Do not prepare stock solutions for storage. Equilibrate vial to room temperature before opening and use it immediately.The product is typically not visible in the vial.

Referências selecionadas:
Okerberg et al. (2019) Chemoproteomics Using Nucleotide Acyl Phosphates Reveals an ATP Binding Site at the Dimer Interface of Procaspase-6. Biochemistry. doi:10.1021/acs.biochem.9b00290.

Nordin et al. (2015) ATP Acyl Phosphate Reactivity Reveals Native Conformations of Hsp90 Paralogs and Inhibitor Target Engagement. Biochemistry. 54 (19):3024.

Adachi et al. (2014) Proteome-wide discovery of unknown ATP-binding proteins and kinase inhibitor target proteins using an ATP probe. J. Proteome Res. 13 (12):5461.

Edgar et al. (2014) A combination of SILAC and nucleotide acyl phosphate labelling reveals unexpected targets of the Rsk inhibitor BI-D1870. Biosci. Rep. 34 (1):e00091.