EDA-GDP-ATTO-488

2'/3'-O-(2-Aminoethyl-carbamoyl)-Guanosine-5'-diphosphate, labeled with ATTO 488, Triethylammonium salt

Catálogo Nº Apresentação Preço (R$) Comprar / Observação
NU-840-488 80 μl (1 mM) Sob demanda Adicionar ao Carrinho
Structural formula of EDA-GDP-ATTO-488 (2'/3'-O-(2-Aminoethyl-carbamoyl)-Guanosine-5'-diphosphate, labeled with ATTO 488, Triethylammonium salt)
Structural formula of EDA-GDP-ATTO-488
excitation and emission spectrum of ATTO 488
excitation and emission spectrum of ATTO 488

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 12 months after date of delivery

Fórmula molecular: C38H42N10O21P2S2 (free acid)

Peso molecular: 1100.87 g/mol (free acid)

Pureza: ≥ 95 % (HPLC)

Forma: solution in water

Concentração: 1.0 mM - 1.1 mM

pH: 7.5 ±0.5

Propriedades espectroscópicas: λexc 500 nm, λem 520 nm, ε 90.0 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Referências selecionadas:
Lee et al. (2017) Mechanism of SOS PR-domain autoinhibition revealed by single-molecule assays on native protein from lysate. Nat. Commun. 8:15061.

Christensen et al. (2016) One-way membrane trafficking of SOS in receptor-triggered Ras activation. Nat. Struct. Mol. Biol. 23 (9):838.

Lin et al. (2014) H-Ras forms dimers on membrane surfaces via a protein-protein interface. Proc. Natl. Acad. Sci. USA 111 (8):2996.