XMP

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 12 months after date of delivery

Fórmula molecular: C10H13N4O9P (free acid)

Peso molecular: 364.21 g/mol (free acid)

CAS#: 25899-70-1

Pureza: ≥ 95 % (HPLC)

Forma: solution in water

Concentração: 10 mM - 11 mM

pH: 7.5 ±0.5

Propriedades espectroscópicas: λmax 276 nm, ε 9.6 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Referências selecionadas:
Fulga et al. (2001) SR beta coordinates signal sequence release from SRP with ribosome binding to the translocon. EMBO J. 20 (9):2338.

Legate et al. (2000) Nucleotide-dependent binding of the GTPase domain of the signal recognition particle receptor betasubunit to the alpha-subunit. J. Biol. Chem. 275 (35):27439.

Sakash et al. (2000) The use of nucleotide analogs to evaluate the mechanism of the heterotropic response of Escherichia coli aspartate transcarbamoylase. Protein Sci. 9 (1):53.

Hwang et al. (1999) Structure-based identification of a novel NTPase from Methanococcus jannaschii. Nat. Struct. Biol. 6 (7):691.

Muraoka et al. (1999) Effects of purinenucleotide analogues on microtubule assembly. Cell Struct. Funct. 24 (5):305.

Seifert et al. (1999) Effects of guanine, inosine, and xanthine nucleotides on beta (2)-adrenergic receptor/G (s) interactions: Evidence for multiple receptor conformations. Mol. Pharmacol. 56 (2):348.

Yu et al. (1997) Characterization of a Go alpha mutant that binds xanthine nucleotides. J. Biol. Chem. 272 (29):18015.

Rybin et al. (1996) GTPase activity of Rab5 acts as a timer for endocytic membrane fusion. Nature 383 (6597):266.

Powers et al. (1995) Reciprocal stimulation of GTP hydrolysis by 2 directly interacting GTPases. Science 269 (5229):1422.