2-Hydroxy-ATP

(iso-GTP)

2-Hydroxy-adenosine-5'-triphosphate, Sodium salt

Catálogo Nº Apresentação Preço (R$) Comprar
NU-1173S 50 μl (10 mM)Sob demanda Adicionar ao Carrinho
NU-1173L 5 x 50 μl (10 mM)Sob demanda Adicionar ao Carrinho
Structural formula of 2-Hydroxy-ATP ((iso-GTP), 2-Hydroxy-adenosine-5'-triphosphate, Sodium salt)
Structural formula of 2-Hydroxy-ATP

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 12 months after date of delivery

Fórmula molecular: C10H16N5O14P3 (free acid)

Peso molecular: 523.18 g/mol (free acid)

Pureza: ≥ 95 % (HPLC)

Forma: solution in water

Concentração: 10 mM - 11 mM

pH: 7.5 ±0.5

Propriedades espectroscópicas: λmax 292 nm, ε 11.1 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Formulários:
Inducing C-T mutations during transcription[1]
Hydrolysis byMTH1-protein[2]

Specific Ligands:

Binding to MTH1-protein[2]

Referências selecionadas:
[1] Kamiya et al. (2007) Effects of 8-hydroxy-GTP and 2-hydroxy-ATP on in vitro transcription. Free Radical Biology and Medicine 43 (5):837.

[2] Fujikawa et al. (2001) Human MTH1 protein hydrolyzes the oxidized ribonucleotide, 2-hydroxy-ATP. Nucleic Acids Res. 29 (2):449.