N6-Methyl-dATP

N6-Methyl-2'-deoxyadenosine-5'-triphosphate, Sodium salt

N6-Methyl-2'-dATP

Catálogo Nº Apresentação Preço (R$) Comprar
NU-949S 10 μl (100 mM)Sob demanda Adicionar ao Carrinho
NU-949L 5 x 10 μl (100 mM)Sob demanda Adicionar ao Carrinho
Structural formula of N6-Methyl-dATP (N6-Methyl-2'-deoxyadenosine-5'-triphosphate, Sodium salt)
Structural formula of N6-Methyl-dATP

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 12 months after date of delivery

Fórmula molecular: C11H18N5O12P3 (free acid)

Peso molecular: 505.21 g/mol (free acid)

Pureza: ≥ 95 % (HPLC)

Forma: solution in water

Concentração: 100 mM - 110 mM

pH: 7.5 ±0.5

Propriedades espectroscópicas: λmax 269 nm, ε 15.4 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Referências selecionadas:
Choi et al. (2016) The use of modified and non-natural nucleotides provide unique insights into pro-mutagenic replication catalyzed by polymerase eta. Nucleic Acids Res. 44 (3):1022.

Devadoss et al. (2007) Enhancing the 'A-rule' of translesion DNA synthesis: promutagenic DNA synthesis using modified nucleoside triphosphates. Biochemistry 46 (48):13752.

Ratel et al. (2006) N6-methyladenine: the other methylated base of DNA. Bioessays. 28 (3):309.

Kuwahara et al. (2003) Simultaneous incorporation of three different modified nucleotides during PCR. Nucleic Acids Res. Suppl. 3:37.