8-Oxo-dGDP
8-Hydroxy-dGDP
8-Oxo-2'-deoxyguanosine-5'-diphosphate, Sodium salt
8-Hydroxy-2'-deoxyguanosine-5'-diphosphate, Sodium salt
| Catálogo Nº | Apresentação | Preço (R$) | Comprar |
|---|---|---|---|
| NU-1158S | 20 μl (10 mM) | Sob demanda | Adicionar ao Carrinho |
| NU-1158L | 5 x 20 μl (10 mM) | Sob demanda | Adicionar ao Carrinho |
For general laboratory use.
Envio: shipped on gel packs
Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Validade: 12 months after date of delivery
Fórmula molecular: C10H15N5O11P2 (free acid)
Peso molecular: 443.20 g/mol (free acid)
Pureza: ≥ 95 % (HPLC)
Forma: solution in water
Concentração: 10 mM - 11 mM
pH: 7.5 ±0.5
Propriedades espectroscópicas: λmax 245 nm, ε 12.3 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Referências selecionadas:
Kai et al. (2002) An oxidized nucleotide affects DNA replication through activation of protein kinases in Xenopus egg lysates. Nucl. Acids Res. 30 (2):569.
Canitrot et al. (2000) Nucleotide excision repair DNA synthesis by excess DNA polymerase beta: a potential source of genetic instability in cancer cells. FASEB J. 14 (12):1765.
Nampalli et al. (2000) Efficient synthesis of 8-oxo-dGTP: A mutagenic nucleotide. Bioorg. Med. Chem. Lett. 10 (15):1677.