3'-dGTP

3'-Deoxyguanosine-5'-triphosphate, Sodium salt

Catálogo Nº Apresentação Preço (R$) Comprar
NU-1145S 50 μl (10 mM)Sob demanda Adicionar ao Carrinho
NU-1145L 5 x 50 μl (10 mM)Sob demanda Adicionar ao Carrinho
Structural formula of 3'-dGTP (3'-Deoxyguanosine-5'-triphosphate, Sodium salt)
Structural formula of 3'-dGTP

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 12 months after date of delivery

Fórmula molecular: C10H16N5O13P3 (free acid)

Peso molecular: 507.18 g/mol (free acid)

CAS#: 55968-37-1

Pureza: ≥ 95 % (HPLC)

Forma: solution in water

Concentração: 10 mM - 11 mM

pH: 7.5 ±0.5

Propriedades espectroscópicas: λmax 252 nm, ε 13.7 L mmol-1 cm-1 (Tris-HCl pH 7.5)

Formulários:
Microtubule assembly[1]
Hydrolysis by tubulin and proteins[1]

Specific Ligands:

Affinity to RNA polymerase I and II[2]

Affinity to DNA primase[2]

Referências selecionadas:
[1] Hamel et al. (1984) Deoxyguanosine nucleotide analogues: potent stimulators of microtubule nucleation with reduced affinity for the exchangeable nucleotide site of tubulin. Biochemistry 23 (22):5314.

[2] Shunji Izuta et al. (1996) 3'-Deoxyribonucleotides inhibit Eukaryotic DNA Primase1. J. Biochem. 119 (6):1038.

Rasmussen et al. (1993) In vivo transcriptional pausing and cap formation on three Drosophila heat schock genes. Proc. Natl. Acad. Sci. USA 90:7923.

Hamel et al. (1976) Interactions of Guanosine Triphosphate Analogues with Elongation Factor G of Eschericha coli. J. Biochem. 63:13894.