5-Carboxy-dC
cadC, 5-Carboxy-2'-deoxycytidine
| Catálogo Nº | Apresentação | Preço (R$) | Comprar / Observação |
|---|---|---|---|
| N-1067-5 | 5 mg | Sob demanda | Adicionar ao Carrinho |
For research use only!
Envio: shipped at ambient temperature
Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Validade: 24 months after date of delivery
Fórmula molecular: C10H13N3O6
Peso molecular: 271.23 g/mol
Pureza: ≥ 95 % (HPLC)
Forma: solid
Solubilidade: water, methanol
Propriedades espectroscópicas: λmax 280 nm, ε 7.6 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Formulários:
Metabolism of dC substituted at position 5[1]
Incorporation into DNA[2]
functional and conformational influence of cytosine modifications[3]
Referências selecionadas:
[1] Schiesser (2013) Deamination, Oxidation, and C-C Bond Cleavage Reactivity of 5-Hydroxymethylcytosine, 5-Formylcytosine, and 5-Carboxycytosine. J. Am. Chem. Soc. 135:14593.
[2] Schroeder (2014) Synthesis of a DNA promoter segment containing all four epigenetic nucleosides: 5-Methyl-, 5-hydroxymethyl-, 5-formyl-, and 5-carboxy-2'-deoxycytidine. Angew. Chem. Int. Ed. 53: 315.
[3] Sumino (2008) Synthesis and properties of oligodeoxynucleotides containing 5-carboxy-2'-deoxycytidines. Bioorg. Med. Chem. Lett. 18:274.