AMP-α-F
(ApF)
Adenosine-5'-(α-fluoro)-monophosphate, Sodium salt
Adenosine-5'-(1-fluoro)-monophosphate, Sodium salt
| Catálogo Nº | Apresentação | Preço (R$) | Comprar |
|---|---|---|---|
| NU-943-5 | 5 mg | Sob demanda | Adicionar ao Carrinho |
| NU-943-25 | 25 mg | Sob demanda | Adicionar ao Carrinho |
For general laboratory use.
Envio: shipped on gel packs
Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Validade: 12 months after date of delivery
Fórmula molecular: C10H13FN5O6P (free acid)
Peso molecular: 349.21 g/mol (free acid)
CAS#: 19375-33-8 (free acid), 15503-75-0 (sodium salt)
Pureza: ≥ 95 % (HPLC)
Forma: solid
Propriedades espectroscópicas: λmax 259 nm, ε 15.4 L mmol-1 cm-1 (Tris-HCl pH 7.5)
Formulários:
Substrate for snake venom phosphodiesterase [1,2]
Substrate for Fhit proteins [3]
Inhibitor of adenlyate kinase [4]
Referências selecionadas:
[1] Baranowski et al. (2016) A fluorescent HTS assay for phosphohydrolases based on nucleoside 5'-fluorophosphates: its application in screening for inhibitors of mRNA decapping scavenger and PDE-I. Org. Biomol. Chem. 14 (20):4595.
[2] Baranowski et al. (2015) Synthesis of fluorophosphate nucleotide analogues and their characterization as tools for ¹⁹F NMR studies. J. Org. Chem. 80 (8):3982.
[3] Guranowski et al. (2008) Fhit proteins can also recognize substrates other than dinucleoside polyphosphates. FEBS Lett. 582 (20):3152.
[4] Scoblov et al. (1996) Modified nucleotides as substrates and inhibitors of adenylate kinase from different sources. FEBS Lett. 395 (2-3):283.