Mant-ITPγS
2'/3'-O-(N-Methyl-anthraniloyl)-inosine-5'-(γ-thio)-triphosphate, Triethylammonium salt
| Catálogo Nº | Apresentação | Preço (R$) | Comprar / Observação |
|---|---|---|---|
| NU-981 | 150 μl (10 mM) | Sob demanda | Adicionar ao Carrinho |
For general laboratory use.
Envio: shipped on dry ice
Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.
Validade: 6 months after date of delivery
Fórmula molecular: C18H22N5O14P3S (free acid)
Peso molecular: 657.38 g/mol (free acid)
Pureza: ≥ 90 % (HPLC)
Forma: solution in water
Concentração: 10 mM - 11 mM
pH: 7.5 ±0.5
Propriedades espectroscópicas: λmax 279/355 nm, ε 20.5/5.7 L mmol-1 cm-1 (Tris-HCl pH 7.5), λexc 355 nm, λem 448 nm
Referências selecionadas:
Seifert et al. (2012) Inhibitors of membranous adenylyl cyclases. Trends Pharmacol. Sci. 33 (2):64.
Hübner et al. (2011) Effect of MANT-nucleotides on L-type calcium currents in murine cardiomyocytes. J. Naunyn Schmiedebergs Arch. Pharmacol. 383 (4):573.
Erdorf et al. (2011) Pharmacological characterization of adenylyl cyclase isoforms in rabbit kidney membranes. J. Naunyn Schmiedebergs Arch. Pharmacol. 383 (4):357.
Goettle et al. (2009) Characterization of Mouse Heart Adenylyl Cyclase. J. Pharmacol. Exp. Ther. 329 (3):1156.
Goettle et al. (2007) Molecular analysis of the interaction of Bordetella pertussis adenylyl cyclase with fluorescent nucleotides. Molecular Pharmacology 72 (3):526.
Gille et al. (2004) Differential Inhibition of Adenylyl Cyclase Isoforms and Soluble Guanylyl Cyclase by Purine and Pyrimidine Nucleotides. J. Biol. Chem. 279 (19):19955.