Ant-GTP

2'/3'-O-Anthraniloyl-guanosine-5'-triphosphate, Triethylammonium salt

Catálogo Nº Apresentação Preço (R$) Comprar
NU-230S 150 μl (10 mM)Sob demanda Adicionar ao Carrinho
NU-230L 5 x 150 μl (10 mM)Sob demanda Adicionar ao Carrinho
Structural formula of Ant-GTP (2'/3'-O-Anthraniloyl-guanosine-5'-triphosphate, Triethylammonium salt)
Structural formula of Ant-GTP

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 12 months after date of delivery

Fórmula molecular: C17H21N6O15P3 (free acid)

Peso molecular: 642.30 g/mol (free acid)

CAS#: 85287-50-9 (3'-isomer)

Pureza: ≥ 95 % (HPLC)

Forma: solution in water

Concentração: 10 mM - 11 mM

pH: 7.5 ±0.5

Propriedades espectroscópicas: λmax 258/332 nm, ε 9.8/4.6 L mmol-1 cm-1 (Tris-HCl pH 7.5), λexc 332 nm, λem 423 nm

Referências selecionadas:
Gunawardana et al. (2015) Efficient preparation and properties of mRNAs containing a fluorescent cap analog: Anthraniloyl-m7GpppG Translation (Austin). 3 (1):e988538.

Pinto et al. (2011) Structure-activity relationships for the interactions of 2'- and 3'- (O)- (N-methyl)anthraniloyl-substituted purine and pyrimidine nucleotides with mammalian adenylyl cyclases. Biochem. Pharmacol. 82 (4):358.

Taha et al. (2009) Molecular Analysis of the Interaction of Anthrax Adenylyl Cyclase Toxin, Edema Factor, with 2’ (3’)-O- (N- (methyl)anthraniloyl)-Substituted Purine and Pyrimidine Nucleotides. Molecular Pharmacology 75 (3):693.

Goettle et al. (2007) Molecular analysis of the interaction of Bordetella pertussis adenylyl cyclase with fluorescent nucleotides. Molecular Pharmacology 72 (3):526.