Mant-AMP

2'/3'-(N-Methyl-anthraniloyl)-adenosine-5'-monophosphate, Triethylammonium salt

Catálogo Nº Apresentação Preço (R$) Comprar
NU-236S 150 μl (10 mM)Sob demanda Adicionar ao Carrinho
NU-236L 5 x 150 μl (10 mM)Sob demanda Adicionar ao Carrinho
Structural formula of Mant-AMP (2'/3'-(N-Methyl-anthraniloyl)-adenosine-5'-monophosphate, Triethylammonium salt)
Structural formula of Mant-AMP

For general laboratory use.

Envio: shipped on gel packs

Condições de armazenamento: store at -20 °C
Short term exposure (up to 1 week cumulative) to ambient temperature possible.

Validade: 12 months after date of delivery

Fórmula molecular: C18H21N6O8P (free acid)

Peso molecular: 480.37 g/mol (free acid)

Pureza: ≥ 95 % (HPLC)

Forma: solution in water

Concentração: 10 mM - 11 mM

pH: 7.5 ±0.5

Propriedades espectroscópicas: λmax 255/355 nm, ε 23.3/5.8 L mmol-1 cm-1 (Tris-HCl pH 7.5), λexc 355 nm, λem 448 nm

Formulários:
Stopped-flow kinetic studies[1, 2]
Analysis of conformational changes[1]

Specific Ligands:

Pyrophosphatase mtCBS[1]

Helicase DnaB[2]

Referências selecionadas:
[1] Jaemsen et al. (2010) Nucleotide- and substrate-induced conformational transitions in the CBS domain-containing pyrophosphatase of Moorella thermoacetica. Biochemistry 49:1005.

[2] Bujalowski et al. (2000) Kinetic mechanism of nucleotide cofactor binding to Escherichia coli replicative helicase DnaB protein. Stopped-flow kinetic studies using fluorescent, ribose-, and base-modified nucleotide analogues. Biochemistry 39:2106.

Wang et al. (2011) Charge isomers of myelin basic protein: structure and interactions with membranes, nucleotide analogues, and calmodulin. PLoS One. 6 (5):e19915.

Lísal et al. (2008) Cooperative Mechanism of RNA Packaging Motor. The Journal of biological chemistry 280 (24):23157.

Hiratsuka et al. (1983) New Ribose-modified Fluorescent Analogs of Adenine and Guanine Nucleotides Available as Substrates for Various Enzxmes. Biochim Biophys Acta 742:496.